{"id":10843,"date":"2016-03-05T17:30:56","date_gmt":"2016-03-05T17:30:56","guid":{"rendered":"https:\/\/clone.arsacs.com\/sacsin-chaperone-activity-project-progress\/"},"modified":"2026-03-16T18:07:58","modified_gmt":"2026-03-16T22:07:58","slug":"sacsin-chaperone-activity-project-progress","status":"publish","type":"post","link":"https:\/\/arsacs.com\/fr\/sacsin-chaperone-activity-project-progress\/","title":{"rendered":"&#8220;Sacsin Chaperone Activity&#8221; project progress"},"content":{"rendered":"\"Sacsin Chaperone Activity\" project progress. Dr Jason Young's project funded by the Foundation is to examine the ARSACS mutations in the J-HEPN fragment of Sacsin, to engineer Hsc70 to potentially identify sacsin-directed substratesand to address whether Sacsin promotes degradation of neurofilament heavy subunit (NFH).<a href=\"https:\/\/arsacs.com\/fr\/files\/Young_Progress_Feb2016.pdf\/\" target=\"_blank\" rel=\"noopener noreferrer\">\"Sacsin Chaperone Activity\" project progress<\/a>\n\n<a href=\"\/fr\/current\/\">En savoir plus<\/a>","protected":false},"excerpt":{"rendered":"<p>&#8220;Sacsin Chaperone Activity&#8221; project progress. Dr Jason Young&#8217;s project funded by the Foundation is to examine the ARSACS mutations in the J-HEPN fragment of Sacsin, to engineer Hsc70 to potentially identify sacsin-directed substratesand to address whether Sacsin promotes degradation of neurofilament heavy subunit (NFH).&#8221;Sacsin Chaperone Activity&#8221; project progress Read more<\/p>","protected":false},"author":3,"featured_media":9110,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-10843","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-archives"],"_links":{"self":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/10843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/comments?post=10843"}],"version-history":[{"count":1,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/10843\/revisions"}],"predecessor-version":[{"id":24176,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/10843\/revisions\/24176"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/media\/9110"}],"wp:attachment":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/media?parent=10843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/categories?post=10843"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/tags?post=10843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}