{"id":11162,"date":"2018-07-27T21:50:22","date_gmt":"2018-07-27T21:50:22","guid":{"rendered":"https:\/\/clone.arsacs.com\/exploring-neuronal-roles-for-sacsin-from-dendritic-spines-to-neuronal-polarity-dr-bernard-brais\/"},"modified":"2026-03-16T18:10:07","modified_gmt":"2026-03-16T22:10:07","slug":"exploring-neuronal-roles-for-sacsin-from-dendritic-spines-to-neuronal-polarity-dr-bernard-brais-2","status":"publish","type":"post","link":"https:\/\/arsacs.com\/fr\/exploring-neuronal-roles-for-sacsin-from-dendritic-spines-to-neuronal-polarity-dr-bernard-brais-2\/","title":{"rendered":"Exploring Neuronal Roles for Sacsin: from Dendritic Spines to Neuronal Polarity- Dr. Bernard Brais"},"content":{"rendered":"The focus will be on\n\nAim 1. The objective is to submit a paper that will elucidate the role of Sacsin and EndoB2 in dendritic spines that will include our BioID results.\n\nAim 2.  We will explore  if a neuronal polarity defect in cytoskeletal protein trafficking might also be an important aspect of\nARSACS pathophysiology.\n\nDuration: One year\nGrant $80,000\n\nContact\n\n<div id=\"attachment_192\" style=\"width: 160px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-192\" src=\"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Brais_2015-150x150-2.jpg\" alt=\"Dr. Bernard Brais\" width=\"150\" height=\"150\" class=\"size-thumbnail wp-image-192\"><p id=\"caption-attachment-192\" class=\"wp-caption-text\">Dr. Bernard Brais<\/p><\/div>\n\nDr. Bernard Brais, co-director of the neuromuscular group of the Montreal Neurological Institute and Hospital\n3801 University Street Montreal, Quebec, Canada H3A 2B4\nTel:(514)-398-3334; Email: bernard.brais@mcgill.ca","protected":false},"excerpt":{"rendered":"<p>The focus will be on Aim 1. The objective is to submit a paper that will elucidate the role of Sacsin and EndoB2 in dendritic spines that will include our BioID results. Aim 2. We will explore if a neuronal polarity defect in cytoskeletal protein trafficking might also be an important aspect of ARSACS pathophysiology. [&#8230;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[],"class_list":["post-11162","post","type-post","status-publish","format-standard","hentry","category-research-2018"],"_links":{"self":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/11162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/comments?post=11162"}],"version-history":[{"count":2,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/11162\/revisions"}],"predecessor-version":[{"id":24421,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/11162\/revisions\/24421"}],"wp:attachment":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/media?parent=11162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/categories?post=11162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/tags?post=11162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}