{"id":11602,"date":"2016-03-29T04:57:06","date_gmt":"2016-03-29T04:57:06","guid":{"rendered":"https:\/\/clone.arsacs.com\/identification-of-cellular-mechanisms-underlying-tps-100-rescue-of-motor-function-in-arsacs-mice-dr-alanna-watt-and-dr-anne-mckinney\/"},"modified":"2016-03-29T04:57:06","modified_gmt":"2016-03-29T04:57:06","slug":"identification-of-cellular-mechanisms-underlying-tps-100-rescue-of-motor-function-in-arsacs-mice-dr-alanna-watt-and-dr-anne-mckinney","status":"publish","type":"post","link":"https:\/\/arsacs.com\/fr\/identification-of-cellular-mechanisms-underlying-tps-100-rescue-of-motor-function-in-arsacs-mice-dr-alanna-watt-and-dr-anne-mckinney\/","title":{"rendered":"&#8220;Identification of cellular mechanisms underlying TPS-100 rescue of motor function in ARSACS mice&#8221; &#8211; Dr. Alanna Watt and Dr. Anne McKinney."},"content":{"rendered":"<p>The McKinney and Watt labs, which are located in close proximity in the Bellini Life Sciences Complex and who already share a mouse colony of ARSACS mice (Sacs-\/-) will determine the physiological mode of action of TPS-100 a pharma and aminopyridines on Purkinje cell function, including synaptic input and output. They will work closely together, to elucidate the mechanism of action of TPS-100, which has been shown to rescue motor function in ARSACS mice (personal communication,B. Brais), or similar other therapeutic agents. This work will advance the goal of a therapeutic intervention for ARSACS.<\/p>\n<p>Duration: two years<br \/>\nGrant: $140,000 per year<br \/>\nContacts:<\/p>\n<div id=\"attachment_132\" style=\"width: 160px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-132\" class=\"size-thumbnail wp-image-132\" src=\"https:\/\/arsacs.com\/wordpress\/wp-content\/uploads\/2016\/03\/watt-1-150x150.jpg\" alt=\"Dr. Alanna Watt\" width=\"150\" height=\"150\" \/><p id=\"caption-attachment-132\" class=\"wp-caption-text\">Dr. Alanna Watt<\/p><\/div>\n<p>Dr. Alanna Watt, Department of Biology McGill University Bellini Life Sciences Bldg.<br \/>\n3469 Sir William Osler, Montreal, Quebec Canada H3G 0B1 Office: Rm. 265 | Lab: Rm. 257<br \/>\nTel: (514)-398-2806; Fax: (514)-398-5069; Email: <a href=\"mailto:alanna.watt@mcgill.ca\">alanna.watt@mcgill.ca<\/a><\/p>\n<div id=\"attachment_186\" style=\"width: 160px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-186\" class=\"size-thumbnail wp-image-186\" src=\"https:\/\/arsacs.com\/wordpress\/wp-content\/uploads\/2016\/03\/Anne-McKinney-150x150.jpg\" alt=\"Anne McKinney\" width=\"150\" height=\"150\" \/><p id=\"caption-attachment-186\" class=\"wp-caption-text\">Anne McKinney<\/p><\/div>\n<p>Dr. Anne McKinney, Department of Pharmacology and Therapeutics,<br \/>\nMcGill University Bellini Life Sciences Bldg<br \/>\n3469 Sir William Osler, Montreal, Quebec Canada H3G 0B1<br \/>\nTel: (514)-398-5685; Fax: (514)-398-2045; Email: <a href=\"mailto:anne.mckinney@mcgill.ca\">anne.mckinney@mcgill.ca<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The McKinney and Watt labs, which are located in close proximity in the Bellini Life Sciences Complex and who already share a mouse colony of ARSACS mice (Sacs-\/-) will determine the physiological mode of action of TPS-100 a pharma and aminopyridines on Purkinje cell function, including synaptic input and output. They will work closely together, [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[23],"tags":[],"class_list":["post-11602","post","type-post","status-publish","format-standard","hentry","category-recherche-2016"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>&quot;Identification of cellular mechanisms underlying TPS-100 rescue of motor function in ARSACS mice&quot; - Dr. Alanna Watt and Dr. Anne McKinney. - ARSACS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/arsacs.com\/fr\/identification-of-cellular-mechanisms-underlying-tps-100-rescue-of-motor-function-in-arsacs-mice-dr-alanna-watt-and-dr-anne-mckinney\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"&quot;Identification of cellular mechanisms underlying TPS-100 rescue of motor function in ARSACS mice&quot; - Dr. Alanna Watt and Dr. Anne McKinney. - ARSACS\" \/>\n<meta property=\"og:description\" content=\"The McKinney and Watt labs, which are located in close proximity in the Bellini Life Sciences Complex and who already share a mouse colony of ARSACS mice (Sacs-\/-) will determine the physiological mode of action of TPS-100 a pharma and aminopyridines on Purkinje cell function, including synaptic input and output. 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