{"id":11790,"date":"2018-07-27T21:43:08","date_gmt":"2018-07-27T21:43:08","guid":{"rendered":"https:\/\/clone.arsacs.com\/therapeutic-approaches-for-arsacs-dr-benoit-gentil-and-dr-heather-durham\/"},"modified":"2018-07-27T21:43:08","modified_gmt":"2018-07-27T21:43:08","slug":"therapeutic-approaches-for-arsacs-dr-benoit-gentil-and-dr-heather-durham","status":"publish","type":"post","link":"https:\/\/arsacs.com\/fr\/therapeutic-approaches-for-arsacs-dr-benoit-gentil-and-dr-heather-durham\/","title":{"rendered":"Therapeutic Approaches for ARSACS- Dr. Benoit Gentil and Dr. Heather Durham"},"content":{"rendered":"<p>The current proposal proposes to capitalize on our discoveries and to move forward in two<br \/>\ndirections. First, pursue the protein\/gene replacement approach until it produces a preclinical proof of<br \/>\nconcept that includes a translatable delivery method. Second, assess the therapeutic potential of HDAC<br \/>\ninhibitors for ARSACS. Although not included as a specific aim in this proposal, developments with<br \/>\nHSP inducers in the ALS study will be applied in the ARSACS models.<\/p>\n<p>Duration: One year<br \/>\nGrant: $80,000<\/p>\n<p>Contacts<br \/>\n<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Durham_Benoit_Nov_2017-150x150-2.jpg\" alt=\"\" width=\"150\" height=\"150\" class=\"alignleft size-thumbnail wp-image-3643\"><br \/>\nDR. Benoit Gentil<br \/>\nRoom 649, Montreal Neurological Institute<br \/>\n3801 University street, Montreal, H3A 2B4<br \/>\nTel: 514-398-8509; Fax: 514-398-1509; email: benoit.gentil@mcgill.ca<\/p>\n<p>Dr. Heather Durham<br \/>\nRoom 649, Montreal Neurological Institute<br \/>\n3801 University street, Montreal, H3A 2B4<br \/>\nTel: 514-398-8509; Fax: 514-398-1509; email: heather.durham@mcgill.ca<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The current proposal proposes to capitalize on our discoveries and to move forward in two directions. First, pursue the protein\/gene replacement approach until it produces a preclinical proof of concept that includes a translatable delivery method. Second, assess the therapeutic potential of HDAC inhibitors for ARSACS. Although not included as a specific aim in this [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[25],"tags":[],"class_list":["post-11790","post","type-post","status-publish","format-standard","hentry","category-recherche-2018"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Therapeutic Approaches for ARSACS- Dr. Benoit Gentil and Dr. Heather Durham - ARSACS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/arsacs.com\/fr\/therapeutic-approaches-for-arsacs-dr-benoit-gentil-and-dr-heather-durham\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Therapeutic Approaches for ARSACS- Dr. Benoit Gentil and Dr. Heather Durham - ARSACS\" \/>\n<meta property=\"og:description\" content=\"The current proposal proposes to capitalize on our discoveries and to move forward in two directions. 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