{"id":11891,"date":"2018-07-27T21:50:22","date_gmt":"2018-07-27T21:50:22","guid":{"rendered":"https:\/\/clone.arsacs.com\/sacins-role-in-synapses-early-pathological-changes-in-arsacs-dr-bernard-brais\/"},"modified":"2026-03-16T18:10:08","modified_gmt":"2026-03-16T22:10:08","slug":"sacins-role-in-synapses-early-pathological-changes-in-arsacs-dr-bernard-brais","status":"publish","type":"post","link":"https:\/\/arsacs.com\/fr\/sacins-role-in-synapses-early-pathological-changes-in-arsacs-dr-bernard-brais\/","title":{"rendered":"Le r\u00f4le de la sacine dans les synapses : modifications pathologiques pr\u00e9coces dans l'ARSACS \u2013 Dr Bernard Brais"},"content":{"rendered":"<p class=\"m_-7143807540727008346MsoListParagraph\"><b>Aim 1: Sacsin\u2019s role in dendritic spines morphology<u><\/u><u><\/u><\/b><\/p>\n<p class=\"m_-7143807540727008346MsoListParagraph\"><b>Aim 1.1<\/b>.\u00a0<i>Assess the impact of sacsin loss on dendritic spines morphology<u><\/u><u><\/u><\/i><\/p>\n<p class=\"m_-7143807540727008346MsoListParagraph\"><b>Aim 1.2.\u00a0<\/b><i>Assess the role of sacsin partners on dendritic spine morphology.<u><\/u><u><\/u><\/i><\/p>\n<p class=\"m_-7143807540727008346MsoListParagraph\"><b>Aim 1.3.\u00a0<\/b><i>Study spine morphology in Sacs<\/i><i>-\/-\u00a0<\/i><i>mice.<u><\/u><u><\/u><\/i><\/p>\n<p class=\"m_-7143807540727008346MsoListParagraph\"><b>Aim 1.4.\u00a0<\/b><i>Assess the role of sacsin on receptor internalization<\/i><\/p>\n\nGrant $100,000\n\nContact\n\n<img loading=\"lazy\" decoding=\"async\" class=\"size-thumbnail wp-image-192\" src=\"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Brais_2015-150x150-2.jpg\" alt=\"Dr. Bernard Brais\" width=\"150\" height=\"150\" \/>\n\nDr. Bernard Brais, co-director of the neuromuscular group of the Montreal Neurological Institute and Hospital\n3801 University Street Montreal, Quebec, Canada H3A 2B4\nTel:(514)-398-3334; Email: bernard.brais@mcgill.ca","protected":false},"excerpt":{"rendered":"<p>Aim 1: Sacsin\u2019s role in dendritic spines morphology Aim 1.1.\u00a0Assess the impact of sacsin loss on dendritic spines morphology Aim 1.2.\u00a0Assess the role of sacsin partners on dendritic spine morphology. Aim 1.3.\u00a0Study spine morphology in Sacs-\/-\u00a0mice. Aim 1.4.\u00a0Assess the role of sacsin on receptor internalization Grant $100,000 Contact Dr. Bernard Brais, co-director of the neuromuscular [&#8230;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[],"class_list":["post-11891","post","type-post","status-publish","format-standard","hentry","category-recherche-2019"],"_links":{"self":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/11891","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/comments?post=11891"}],"version-history":[{"count":2,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/11891\/revisions"}],"predecessor-version":[{"id":24424,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/11891\/revisions\/24424"}],"wp:attachment":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/media?parent=11891"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/categories?post=11891"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/tags?post=11891"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}