{"id":15947,"date":"2021-10-29T20:13:07","date_gmt":"2021-10-30T00:13:07","guid":{"rendered":"https:\/\/arsacs.com\/?p=15947"},"modified":"2023-11-16T10:31:13","modified_gmt":"2023-11-16T15:31:13","slug":"charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin","status":"publish","type":"post","link":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/","title":{"rendered":"\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel"},"content":{"rendered":"<p>It is well established in neurodegenerative diseases that early therapeutic intervention &#8211; ideally before neurodegenerative cascades begin to breakdown neuronal function &#8211; is key to the success of disease-modifying therapies. Yet we do not understand the early molecular and cellular changes that precede the loss of neurons in ARSACS, let alone biomarkers which would allow us to track the earliest stages of the disease. Understanding the early changes in ARSACS will clarify fundamental molecular deficiencies, and motivate preemptive therapeutic strategies aimed at delaying, or possibly preventing, the progression of this disease.<\/p>\n<p>The goals of this project are to generate a cross-species map of the developmental trajectory of ARSACS through the lens of molecular and cellular deficits in the ARSACS mouse model, and readily accessible fluid biomarkers in mice and human patients. This paired longitudinal study design will allow us to mechanistically anchor readily available fluid biomarkers with early cellular abnormalities in the ARSACS brain.<\/p>\n<p>Grant: $80,000 ( first year of the project)<\/p>\n<p>Duration : 2 year project<\/p>\n<p>Contacts:<\/p>\n<p style=\"padding-left: 80px;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-11125 alignleft\" src=\"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Matthis_Synofzik-2.jpg\" alt=\"\" width=\"128\" height=\"128\"><\/p>\n<p style=\"padding-left: 80px;\">Dr. Matthis Synofzik<\/p>\n<p style=\"padding-left: 40px;\">Hertie-Institute for Clinical Brain Research&nbsp;<br>Hoppe-Seyler- Strasse 3, 72076&nbsp; Tubingen, Germany&nbsp;&nbsp;<\/p>\n<p>email: matthis.synofzik@uni.tuebingen.de<\/p>\n<p><\/p>\n<p style=\"text-align: left; padding-left: 80px;\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-16105 alignleft\" src=\"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/12\/David_Mengel-HF-cropped-1-225x300.jpg\" alt=\"\" width=\"130\" height=\"173\">Dr. David Mengel&nbsp;<\/p>\n<p style=\"padding-left: 200px;\">Hertie-Institute for Clinical Brain Research&nbsp;<br>Hoppe-Seyler- Strasse 3, 72076&nbsp; Tubingen, Germany&nbsp;&nbsp;<\/p>\n<p style=\"padding-left: 160px;\">email: david.mengel@uni.tuebingen.de<\/p>\n<p><\/p>\n<p style=\"text-align: left; padding-left: 80px;\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-11491 alignleft\" src=\"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Justin-Wolter1-e1604075278293.jpg\" alt=\"\" width=\"133\" height=\"200\"><\/p>\n<p><\/p>\n<p style=\"text-align: left; padding-left: 80px;\">Dr. Justin Wolter&nbsp;<\/p>\n<p style=\"text-align: left; padding-left: 40px;\">Marie Ellen Jones Building CB#7250<br>116 Manning Dr. Chapel Hill, NC, US 27599<\/p>\n<p style=\"text-align: left;\">email: justin_wolter@med.unc.edu<\/p>\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>It is well established in neurodegenerative diseases that early therapeutic intervention &#8211; ideally before neurodegenerative cascades begin to breakdown neuronal function &#8211; is key to the success of disease-modifying therapies. Yet we do not understand the early molecular and cellular changes that precede the loss of neurons in ARSACS, let alone biomarkers which would allow [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[85],"tags":[],"class_list":["post-15947","post","type-post","status-publish","format-standard","hentry","category-recherche-2021"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel - ARSACS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel - ARSACS\" \/>\n<meta property=\"og:description\" content=\"It is well established in neurodegenerative diseases that early therapeutic intervention &#8211; ideally before neurodegenerative cascades begin to breakdown neuronal function &#8211; is key to the success of disease-modifying therapies. Yet we do not understand the early molecular and cellular changes that precede the loss of neurons in ARSACS, let alone biomarkers which would allow [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/\" \/>\n<meta property=\"og:site_name\" content=\"ARSACS\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/profile.php?id=100044457429916\" \/>\n<meta property=\"article:published_time\" content=\"2021-10-30T00:13:07+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-11-16T15:31:13+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Matthis_Synofzik-2.jpg\" \/>\n<meta name=\"author\" content=\"ARSACS\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ARSACS\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/\"},\"author\":{\"name\":\"ARSACS\",\"@id\":\"https:\\\/\\\/arsacs.com\\\/#\\\/schema\\\/person\\\/93b66d6b897bfa131622d04b767b15f1\"},\"headline\":\"\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel\",\"datePublished\":\"2021-10-30T00:13:07+00:00\",\"dateModified\":\"2023-11-16T15:31:13+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/\"},\"wordCount\":261,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/arsacs.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/arsacs.com\\\/wp-content\\\/uploads\\\/2021\\\/02\\\/Matthis_Synofzik-2.jpg\",\"articleSection\":[\"Recherche 2021\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/\",\"url\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/\",\"name\":\"\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel - ARSACS\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/arsacs.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/arsacs.com\\\/wp-content\\\/uploads\\\/2021\\\/02\\\/Matthis_Synofzik-2.jpg\",\"datePublished\":\"2021-10-30T00:13:07+00:00\",\"dateModified\":\"2023-11-16T15:31:13+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/#primaryimage\",\"url\":\"https:\\\/\\\/arsacs.com\\\/wp-content\\\/uploads\\\/2021\\\/02\\\/Matthis_Synofzik-2.jpg\",\"contentUrl\":\"https:\\\/\\\/arsacs.com\\\/wp-content\\\/uploads\\\/2021\\\/02\\\/Matthis_Synofzik-2.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/arsacs.com\\\/fr\\\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/arsacs.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/arsacs.com\\\/#website\",\"url\":\"https:\\\/\\\/arsacs.com\\\/\",\"name\":\"Fondation de l'Ataxie Charlevoix-Saguenay\",\"description\":\"Research That Heals\",\"publisher\":{\"@id\":\"https:\\\/\\\/arsacs.com\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/arsacs.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/arsacs.com\\\/#organization\",\"name\":\"ARSACS\",\"url\":\"https:\\\/\\\/arsacs.com\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/arsacs.com\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/arsacs.com\\\/wp-content\\\/uploads\\\/2021\\\/06\\\/logo_ARSACS_fr_flat.png\",\"contentUrl\":\"https:\\\/\\\/arsacs.com\\\/wp-content\\\/uploads\\\/2021\\\/06\\\/logo_ARSACS_fr_flat.png\",\"width\":291,\"height\":84,\"caption\":\"ARSACS\"},\"image\":{\"@id\":\"https:\\\/\\\/arsacs.com\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/profile.php?id=100044457429916\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/arsacs.com\\\/#\\\/schema\\\/person\\\/93b66d6b897bfa131622d04b767b15f1\",\"name\":\"ARSACS\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/e3b226aca332e58d41ec45fa04620bcbd869d2e4e661cacde31eeb3ae6a5708d?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/e3b226aca332e58d41ec45fa04620bcbd869d2e4e661cacde31eeb3ae6a5708d?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/e3b226aca332e58d41ec45fa04620bcbd869d2e4e661cacde31eeb3ae6a5708d?s=96&d=mm&r=g\",\"caption\":\"ARSACS\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel - ARSACS","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/","og_locale":"fr_FR","og_type":"article","og_title":"\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel - ARSACS","og_description":"It is well established in neurodegenerative diseases that early therapeutic intervention &#8211; ideally before neurodegenerative cascades begin to breakdown neuronal function &#8211; is key to the success of disease-modifying therapies. Yet we do not understand the early molecular and cellular changes that precede the loss of neurons in ARSACS, let alone biomarkers which would allow [&hellip;]","og_url":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/","og_site_name":"ARSACS","article_publisher":"https:\/\/www.facebook.com\/profile.php?id=100044457429916","article_published_time":"2021-10-30T00:13:07+00:00","article_modified_time":"2023-11-16T15:31:13+00:00","og_image":[{"url":"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Matthis_Synofzik-2.jpg","type":"","width":"","height":""}],"author":"ARSACS","twitter_card":"summary_large_image","twitter_misc":{"Written by":"ARSACS","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/#article","isPartOf":{"@id":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/"},"author":{"name":"ARSACS","@id":"https:\/\/arsacs.com\/#\/schema\/person\/93b66d6b897bfa131622d04b767b15f1"},"headline":"\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel","datePublished":"2021-10-30T00:13:07+00:00","dateModified":"2023-11-16T15:31:13+00:00","mainEntityOfPage":{"@id":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/"},"wordCount":261,"commentCount":0,"publisher":{"@id":"https:\/\/arsacs.com\/#organization"},"image":{"@id":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/#primaryimage"},"thumbnailUrl":"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Matthis_Synofzik-2.jpg","articleSection":["Recherche 2021"],"inLanguage":"fr-FR"},{"@type":"WebPage","@id":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/","url":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/","name":"\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel - ARSACS","isPartOf":{"@id":"https:\/\/arsacs.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/#primaryimage"},"image":{"@id":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/#primaryimage"},"thumbnailUrl":"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Matthis_Synofzik-2.jpg","datePublished":"2021-10-30T00:13:07+00:00","dateModified":"2023-11-16T15:31:13+00:00","breadcrumb":{"@id":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/"]}]},{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/#primaryimage","url":"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Matthis_Synofzik-2.jpg","contentUrl":"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/Matthis_Synofzik-2.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/arsacs.com\/fr\/charting-the-neurodevelopmental-stage-of-arsacs-neurodevarsacs-a-cross-species-longitudinal-characterization-of-the-early-molecular-changes-in-the-brain-csf-and-blood-drs-justin\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/arsacs.com\/"},{"@type":"ListItem","position":2,"name":"\u201cCharting the neurodevelopmental stage of ARSACS (NeurodevARSACS): A cross-species longitudinal characterization of the early molecular changes in the brain, CSF and blood\u201d- Drs Justin Wolter, Matthis Synofzik and David Mengel"}]},{"@type":"WebSite","@id":"https:\/\/arsacs.com\/#website","url":"https:\/\/arsacs.com\/","name":"Fondation de l'Ataxie Charlevoix-Saguenay","description":"Research That Heals","publisher":{"@id":"https:\/\/arsacs.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/arsacs.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/arsacs.com\/#organization","name":"ARSACS","url":"https:\/\/arsacs.com\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/arsacs.com\/#\/schema\/logo\/image\/","url":"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/06\/logo_ARSACS_fr_flat.png","contentUrl":"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/06\/logo_ARSACS_fr_flat.png","width":291,"height":84,"caption":"ARSACS"},"image":{"@id":"https:\/\/arsacs.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/profile.php?id=100044457429916"]},{"@type":"Person","@id":"https:\/\/arsacs.com\/#\/schema\/person\/93b66d6b897bfa131622d04b767b15f1","name":"ARSACS","image":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/secure.gravatar.com\/avatar\/e3b226aca332e58d41ec45fa04620bcbd869d2e4e661cacde31eeb3ae6a5708d?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/e3b226aca332e58d41ec45fa04620bcbd869d2e4e661cacde31eeb3ae6a5708d?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/e3b226aca332e58d41ec45fa04620bcbd869d2e4e661cacde31eeb3ae6a5708d?s=96&d=mm&r=g","caption":"ARSACS"}}]}},"_links":{"self":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/15947","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/comments?post=15947"}],"version-history":[{"count":9,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/15947\/revisions"}],"predecessor-version":[{"id":17450,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/15947\/revisions\/17450"}],"wp:attachment":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/media?parent=15947"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/categories?post=15947"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/tags?post=15947"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}