{"id":22704,"date":"2025-09-25T14:33:28","date_gmt":"2025-09-25T18:33:28","guid":{"rendered":"https:\/\/www.arsacs.com\/?p=22704"},"modified":"2026-03-16T18:18:22","modified_gmt":"2026-03-16T22:18:22","slug":"redefining-arsacs-exploring-tdp-43-proteinopathy-as-a-novel-pathogenic-mechanism-dr-francois-gros-louis","status":"publish","type":"post","link":"https:\/\/arsacs.com\/fr\/redefining-arsacs-exploring-tdp-43-proteinopathy-as-a-novel-pathogenic-mechanism-dr-francois-gros-louis\/","title":{"rendered":"“Redefining ARSACS: Exploring TDP-43 Proteinopathy as a Novel Pathogenic Mechanism” – Dr Fran\u00e7ois Gros-Louis"},"content":{"rendered":"

<\/p>\n\n\n

Notre projet de recherche vise \u00e0 mieux comprendre l\u2019ARSACS. Gr\u00e2ce \u00e0 une analyse approfondie du cerveau d\u2019un patient d\u00e9c\u00e9d\u00e9 ayant g\u00e9n\u00e9reusement consenti au don d\u2019organes \u00e0 des fins de recherche, nous avons identifi\u00e9 des anomalies similaires \u00e0 celles observ\u00e9es dans d\u2019autres maladies comme la scl\u00e9rose lat\u00e9rale amyotrophique (SLA) et autres maladies du cerveau. Ces r\u00e9sultats sugg\u00e8rent que certaines causes biologiques pourraient \u00eatre partag\u00e9es entre ces maladies. \u00c0 long terme, cette d\u00e9couverte ouvre la voie \u00e0 de nouvelles pistes pour d\u00e9velopper des traitements adapt\u00e9s dans l\u2019ARSACS.<\/span><\/p>\n

Financement: 100 000$<\/p>\n

Dur\u00e9e : un an<\/p>\n\n\n

\"\"<\/figure>
\n

Dr Fran\u00e7ois Gros-Louis
Centre de recherche du CHU de Qu\u00e9bec - LOEX
H\u00f4pital de l'Enfant-J\u00e9sus (Bureau R-211)
1401 18e rue Qu\u00e9bec, QC
G1J 1Z4<\/p>\n\n\n\n

Coordonn\u00e9es :francois.gros-louis@fmed.ulaval.ca<\/a><\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"

Notre projet de recherche vise \u00e0 mieux comprendre l\u2019ARSACS. Gr\u00e2ce \u00e0 une analyse approfondie du cerveau d\u2019un patient d\u00e9c\u00e9d\u00e9 ayant g\u00e9n\u00e9reusement consenti au don d\u2019organes \u00e0 des fins de recherche, nous avons identifi\u00e9 des anomalies similaires \u00e0 celles observ\u00e9es dans d\u2019autres maladies comme la scl\u00e9rose lat\u00e9rale amyotrophique (SLA) et autres maladies du cerveau. Ces r\u00e9sultats […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-22704","post","type-post","status-publish","format-standard","hentry","category-projets-de-recherche"],"_links":{"self":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/22704","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/comments?post=22704"}],"version-history":[{"count":4,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/22704\/revisions"}],"predecessor-version":[{"id":25139,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/22704\/revisions\/25139"}],"wp:attachment":[{"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/media?parent=22704"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/categories?post=22704"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/arsacs.com\/fr\/wp-json\/wp\/v2\/tags?post=22704"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}