{"id":22718,"date":"2025-09-25T14:33:55","date_gmt":"2025-09-25T18:33:55","guid":{"rendered":"https:\/\/www.arsacs.com\/?p=22718"},"modified":"2025-09-28T14:00:12","modified_gmt":"2025-09-28T18:00:12","slug":"characterization-of-clinically-relevant-compounds-modulating-the-arsacs-associated-phenoty%d1%80%d0%b5-dr-mohan-babu","status":"publish","type":"post","link":"https:\/\/arsacs.com\/fr\/characterization-of-clinically-relevant-compounds-modulating-the-arsacs-associated-phenoty%d1%80%d0%b5-dr-mohan-babu\/","title":{"rendered":"&#8220;Characterization of Clinically Relevant Compounds Modulating the ARSACS associated Phenoty\u0440\u0435&#8221; &#8211; Dr Mohan Babu"},"content":{"rendered":"<p class=\"x_p1\"><span data-olk-copy-source=\"MessageBody\">Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare inherited disease that damages the nervous system and muscles, caused by faults in a protein called sacsin. There is currently no cure, and existing treatments only ease some symptoms. To search for better options, we took skin cells from ARSACS patients, reprogrammed them into brain cells carrying the same faulty protein, and tested many drugs to see if they could reverse the damage. After promising early results, we are now studying exactly how these drugs work, how safe they are, and whether they can reverse symptoms in laboratory models. We are also investigating how well these drugs can reach the brain \u2014 a key hurdle in treating neurological diseases.<\/span><\/p>\n<p>Financement: 100 000$<\/p>\n<p><strong>Ce projet a \u00e9t\u00e9 financ\u00e9 conjointement avec le Richardson Trust Fund qui a contribu\u00e9 50 000$ \u00e0 ce projet.\u00a0<\/strong><\/p>\n<p>Dur\u00e9e : un an<\/p>\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\" style=\"grid-template-columns:25% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"132\" height=\"148\" src=\"https:\/\/arsacs.com\/wp-content\/uploads\/2021\/02\/DrMohanBabu.jpg\" alt=\"Dr. Mohan Babu\" class=\"wp-image-9128 size-full\"\/><\/figure><div class=\"wp-block-media-text__content\">\n<p>Dr Mohan Babu<br>3737 Wascana Parkway<br>University of Regina, Regina<br>Saskatchewan S4S OA2<\/p>\n\n\n\n<p>Coordonn\u00e9es:&nbsp; &nbsp;<a href=\"mailto:mohan.babu@uregina.ca\">mohan.babu@uregina.ca<\/a><\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare inherited disease that damages the nervous system and muscles, caused by faults in a protein called sacsin. There is currently no cure, and existing treatments only ease some symptoms. To search for better options, we took skin cells from ARSACS patients, reprogrammed them into brain [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[35],"tags":[],"class_list":["post-22718","post","type-post","status-publish","format-standard","hentry","category-projets-de-recherche"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>&quot;Characterization of Clinically Relevant Compounds Modulating the ARSACS associated Phenoty\u0440\u0435&quot; - Dr Mohan Babu - ARSACS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/arsacs.com\/fr\/characterization-of-clinically-relevant-compounds-modulating-the-arsacs-associated-phenoty\u0440\u0435-dr-mohan-babu\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"&quot;Characterization of Clinically Relevant Compounds Modulating the ARSACS associated Phenoty\u0440\u0435&quot; - Dr Mohan Babu - ARSACS\" \/>\n<meta property=\"og:description\" content=\"Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare inherited disease that damages the nervous system and muscles, caused by faults in a protein called sacsin. There is currently no cure, and existing treatments only ease some symptoms. 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