Over the next few months, the research team will focus its efforts on :

• Completing the study on the brain and neurons of the hippocampus. Complete the current studies on the histology of the brain of mice to identify where the sacsin is in the neurons population and to produce a model of variable expression of the SACS gene in the neurons of hippocampus. Completing the study of the protein interactors Complete the identification of the proteins which are partners in the sacsin and the characteristics of their physical interactions. cDA: finding the conditions of transfection.

• Establish the ideal conditions and best cell lines for the purpose of surexpression by transfection of the DNAc of the SACS gene.