The research project is to examine the ARSACS mutations in the J-HEPN fragment of sacsin, to engineer Hsc70 to potentially identify sacsin-directed substratesand to address whether sacsin promotes degradation of neurofilament heavy subunit (NFH)
Duration: one year
Grant: $40,431
Contact:
Dr. Jason Young
Dr. Jason Young, Associate Professor Department of Biochemistry
Francesco Bellini Life Sciences Building, 3649 promenade Sir-William-Osler, Office: Room 467; Lab: Room 457, Montreal, Quebec H3G 0B1
Tel:(514)398-2006; Lab: (514)398-5954 Fax:(514)398-7384 Email: ason.young2@mcgill.ca