Autosomal Recessive Spastic Ataxia of Charlevoix–Saguenay (ARSACS) is a rare, inherited neurological disorder that typically begins in early childhood. Symptoms usually appear between ages 2 and 5, affecting motor skills and progressively worsening through adolescence and adulthood—often leading to increased stiffness, difficulty walking, and eventual wheelchair use. The condition impacts the spinal cord and peripheral nerves. Named after the Charlevoix–Saguenay regions of Québec, where it was first identified, ARSACS is now found worldwide and is the second most common recessive ataxia after Friedreich’s ataxia. Dr. Bernard Brais' video presentation on ARSACS. Available in French only.
Research that heals
There is HOPE
The Foundation’s mission is to discover and develop a treatment for the Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS).
Progress has been made over the years in identifying the source of the disorder. Your support is crucial to continue funding high potential projects as well as a clinical trial of a repurposed drug.
Persons with ARSACS
You have been diagnosed with ARSACS, you are not alone. Individuals living with ARSACS are all around the world. There is hope because Research that heals!
Researchers
The Foundation supports ARSACS researchers with funding, tools, and conference support, and seeks partners for preclinical and clinical trials.
Community
The Foundation is supported entirely by private donors and volunteers. We need your support to pursue the mission. Learn different ways you can help!