Continue the investigation of sacsin partners using the BioID assay, using the full length sacsin as well as different sacsin mutants and to further characterize ARSACS fibroblast cytoskeletal disorganization as a cell-based model.
Duration: one year
Grant: $100,000
Contacts:
Dr. Bernard Brais
Dr. Bernard Brais, co-director of the neuromuscular group of the Montreal Neurological Institute and Hospital
3801 University Street Montreal, Quebec, Canada H3A 2B4
Tel:(514)-398-3334; Email: bernard.brais@mcgill.ca
Dr Eric Shoubridge
Dr. Eric Shoubridge, Montreal Neurological Institute and Hospital
3801 University Street Montreal, Quebec, Canada H3A 2B4
Tel: (514)-398-1997; Email: eric.shoubridge@mcgill.ca