Research Tools Available
- Sacs Knock Out mouse (# 033221)
- Sacs Knock In R272C mouse (# 033385)
- Two iPS cell lines are available for research, 1 female and 1 male. These cells are derived from samples taken from people diagnosed with ARSACS (both are homozygous c.8844delT). They have been generated by the Sendai virus method.
- ARSACS Natural History
A large longitudinal study aiming to describe the natural history of ARSACS, with an assessment every 2 years, was conducted from 2011 to 2022. Data relating to coordination, hand strength, walking capacities, balance, overall disease severity are available from a cohort of 90 individuals from Saguenay, Quebec City and Charlevoix.
