A combined transmodal fluid biomarker and neuroimaging study to unravel progression biomarkers for ARSACS, bringing together a unique transatlantic, multi-center consortium which will yield the by far largest , most comprehensive biomarker investigation in ARSACS worlwide, creating combined clinical, biomaterialand multimodal MRI data-sets from 125 ARSACS patients across continents. Fluid biomarker investigations will focus on neurofilaments (NFs), a particularly promissing blood biomarker candidate in ARSACS.
Duration: on year
Grant: $90,000 per year
Contacts:
Dr Matthis Synofzik, Dept. of Neurodegenerative Diseases Hertie-Institute for Clinical Brain Research
Hoppe-Seyler-Strasse 3 72076 Tübingen, Germany
Tel: 49(0)7071-2982060; Fax: 49 (0)7071-2925001; email: matthis.synofzik@uni-tuebingen.de
Dr Roberta La Piana , Montreal Neurological Institute, McGill University
Montreal, Quebec
email: roberta.lapiana@mail.mcgill.ca