Is ARSACS a Tauopathy?- Dr. Paul Chapple

The objectives of the project will be published at a later date. Duration: 3-year funded project Grant: 32,827 pounds Contact : Dr.Paul Chapple, Professor of Molecular Cell BiologyCentre for Endocrinology Barts and The London, Queen Mary’s School of Medicine and...

Hyperphosphorylation in ARSACS. – Dr. Anthony Hickey

To validate the misregulation of tau in ARSACS and establish a platform from which to explore therapeutic targeting of proteins involved in tau pathology as a treatment for ARSACS. Grant: $98,758 Contact: Dr. Anthony Hickey, Director of UNC Catalyst for Rare Diseases,...

Therapeutic Approaches for ARSACS- Dr. Benoit Gentil

To obtain preclinical proof-of-concept for ARSACS treatments based on: 1) a protein/gene replacement approach and 2) drug treatment using HDAC inhibitors. Grant: $100,000 Contact Dr. Benoit Gentil Department of Kinesiology and Physical Education McGill University 475...