“A mouse- human single nuclei-RNA seq profiling in ARSACS cerebellun: understanding how alterations i different cell types contribute to neurodegeneration” – Dr. Francesca Maltecca

This project aims to evaluate the contribution of the different cerebellar cell types to neurodegeneration in ARSACS. In our recent publication (Del Bondio et al., 2023) we showed that in the ARSACS mouse cerebellum there is increased expression of astrocytic...